Compare monoclonal lab reagents for research






Suppliers for Lab Assays

RT (HIV-1)

GWB-FC0114 GenWay Biotech 0.1 mg

RT (HIV-1)

GWB-E6CA8B GenWay Biotech 0.5 ml

HIV-1 Nef

05-011 Sceti 50 ug
Description: The HIV-1 Nef is available in Europe and for worldwide shipping via Gentaur.

HIV-1 Nef

05-012 Sceti 250 ug
Description: The HIV-1 Nef is available in Europe and for worldwide shipping via Gentaur.

HIV-1 p24

E62H002 EnoGene 100ug

HIV-1 p24

E5-00024 EnoGene 1mg

HIV-1 p24

ant-152 ProSpec Tany 0.5mg
Description: Mouse Anti HIV-1 p24

Monoclonal GR monoclonal antibody

AMM00029G Leading Biology 0.05mg 633.6 EUR

Monoclonal TBP monoclonal antibody

APR13720G Leading Biology 0.1ml 633.6 EUR

Monoclonal EZH2 monoclonal antibody

AMM00030G Leading Biology 0.05mg 633.6 EUR

Monoclonal Rsf1 monoclonal antibody

AMM07673G Leading Biology 0.05mg 633.6 EUR

Monoclonal Rsf1 monoclonal antibody

AMM07674G Leading Biology 0.1ml 633.6 EUR

Monoclonal HDAC2 monoclonal antibody

AMM00031G Leading Biology 0.05mg 633.6 EUR

Monoclonal SirT1 monoclonal antibody

APR09951G Leading Biology 0.05mg 580.8 EUR

Monoclonal SirT1 monoclonal antibody

APR09952G Leading Biology 0.1ml 580.8 EUR

Our used TESTs in Pubmed.

Monoclonal TTN Antibody (monoclonal) (M09), Clone: 6H5

AMM04264G Leading Biology 0.1mg 580.8 EUR

Monoclonal VDR Antibody (monoclonal) (M02), Clone: 2F4

AMM04310G Leading Biology 0.1mg 580.8 EUR

Monoclonal WT1 Antibody (monoclonal) (M01), Clone: 2H4

AMM04323G Leading Biology 0.1mg 580.8 EUR

Monoclonal FASN Antibody (monoclonal) (M03), Clone: S1

AMM04516G Leading Biology 0.1mg 580.8 EUR

Monoclonal FH Antibody (monoclonal) (M07), Clone: 5C12

AMM04543G Leading Biology 0.1mg 580.8 EUR

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Suppliers for Lab ELISAs

C106 Dye, 90%

64835 Sisco Laboratories 25 Mg
Description: Part C

Z907 Dye, 95%

82874 Sisco Laboratories 50 Mg
Description: Part C

Z907 Dye, 95%

82874-1 Sisco Laboratories 250 Mg
Description: Part C

MEDIA DYE, RED

F323 PhytoTechnology Laboratories 10G

MEDIA DYE, BLUE

F322 PhytoTechnology Laboratories 10G

Loading Dye (6X)

LD001 Geneaid Biotech each

Loading Dye (6X)

LD010 Geneaid Biotech each

REC-1

ABC-TC0956 AcceGen 1 vial Ask for price

REC-2615 (HCl)

530142 MedKoo Biosciences 10.0mg 295 EUR

Rec FLA-ST

tlrl-flic-10 InvivoGen FR 10 µg 295.05 EUR

Rec FLA-ST

tlrl-flic-50 InvivoGen FR 50 µg 731.85 EUR

rec EGF (human)

4030572.01 Bachem 0.1 mg 102.27 EUR

rec EGF (human)

4030572.05 Bachem 0.5 mg 271.85 EUR

rec EGF (human)

H-7490.0100 Bachem 0.1mg 194.4 EUR

rec EGF (human)

H-7490.0500 Bachem 0.5mg 457.2 EUR

Our used monoclonals in Pubmed.

Monoclonal AES Antibody (monoclonal) (M02), Clone: 10

APR14861G Leading Biology 0.1mg 580.8 EUR

Monoclonal CHP Antibody (monoclonal) (M02), Clone: S2

APR15427G Leading Biology 0.1mg 580.8 EUR

Monoclonal NPY Antibody (monoclonal) (M01), Clone: 3B5

APR07142G Leading Biology 0.1mg 580.8 EUR

Monoclonal PI3 Antibody (monoclonal) (M01), Clone: 3G9

APG02969G Leading Biology 0.1mg 580.8 EUR

Monoclonal VCP Antibody (monoclonal) (M03), Clone: 4A8

APR10683G Leading Biology 0.1mg 580.8 EUR

Compare rec. lab reagents for research




Suppliers for Lab polyclonals

Dye 937

T18985-5mg TargetMol Chemicals 5mg
Description: Dye 937

Dye 993

T18986-10mg TargetMol Chemicals 10mg
Description: Dye 993

Dye 993

T18986-1g TargetMol Chemicals 1g
Description: Dye 993

Dye 993

T18986-1mg TargetMol Chemicals 1mg
Description: Dye 993

Dye 993

T18986-50mg TargetMol Chemicals 50mg
Description: Dye 993

Dye 993

T18986-5mg TargetMol Chemicals 5mg
Description: Dye 993

Dye 937

HY-15422 MedChemExpress 5mg

REC-1

ABC-TC0956 AcceGen 1 vial Ask for price

REC-2615 (HCl)

530142 MedKoo Biosciences 10.0mg 295 EUR

Rec FLA-ST

tlrl-flic-10 InvivoGen FR 10 µg 295.05 EUR

Rec FLA-ST

tlrl-flic-50 InvivoGen FR 50 µg 731.85 EUR

rec EGF (human)

4030572.01 Bachem 0.1 mg 102.27 EUR

rec EGF (human)

4030572.05 Bachem 0.5 mg 271.85 EUR

rec EGF (human)

H-7490.0100 Bachem 0.1mg 194.4 EUR

rec EGF (human)

H-7490.0500 Bachem 0.5mg 457.2 EUR

Our used References in Pubmed.

rec IGF-I (human)

4030778.01 Bachem 100 µg 271.85 EUR

rec IGF-I (human)

4030778.05 Bachem 0.5 mg 1087.59 EUR

rec PDGF BB (human)

4031083.0002 Bachem 2 µg 102.27 EUR

rec PDGF BB (human)

4031083.001 Bachem 10 µg 271.85 EUR

rec TNF-α (human)

4031300.001 Bachem 10 µg 102.27 EUR

Compare monoclonal lab reagents for research



Suppliers for Lab recombinants

rCRAMP (rat)

T40473-1g TargetMol Chemicals 1g
Description: rCRAMP (rat)

rCRAMP (rat)

T40473-1mg TargetMol Chemicals 1mg
Description: rCRAMP (rat)

rCRAMP (rat)

T40473-50mg TargetMol Chemicals 50mg
Description: rCRAMP (rat)

rCRAMP (rat)

T40473-5mg TargetMol Chemicals 5mg
Description: rCRAMP (rat)

BigLEN(rat)

TP2074-10mg TargetMol Chemicals 10mg
Description: BigLEN(rat)

BigLEN(rat)

TP2074-1g TargetMol Chemicals 1g
Description: BigLEN(rat)

BigLEN(rat)

TP2074-1mg TargetMol Chemicals 1mg
Description: BigLEN(rat)

Monoclonal GR monoclonal antibody

AMM00029G Leading Biology 0.05mg 633.6 EUR

Monoclonal TBP monoclonal antibody

APR13720G Leading Biology 0.1ml 633.6 EUR

Monoclonal EZH2 monoclonal antibody

AMM00030G Leading Biology 0.05mg 633.6 EUR

Monoclonal Rsf1 monoclonal antibody

AMM07673G Leading Biology 0.05mg 633.6 EUR

Monoclonal Rsf1 monoclonal antibody

AMM07674G Leading Biology 0.1ml 633.6 EUR

Monoclonal HDAC2 monoclonal antibody

AMM00031G Leading Biology 0.05mg 633.6 EUR

Monoclonal SirT1 monoclonal antibody

APR09951G Leading Biology 0.05mg 580.8 EUR

Monoclonal SirT1 monoclonal antibody

APR09952G Leading Biology 0.1ml 580.8 EUR

Our used antibodies in Pubmed.

TEST TUBE BASKET

T719 PhytoTechnology Laboratories 1EA 42.38 EUR

SNYDER TEST AGAR

S19-119-10kg Alphabiosciences 10 kg 1258.8 EUR

SNYDER TEST AGAR

S19-119-2Kg Alphabiosciences 2 Kg 320.4 EUR

SNYDER TEST AGAR

S19-119-500g Alphabiosciences 500 g 130.8 EUR

HiWater Test Kit

K015-10KT EWC Diagnostics 1 unit 27.8 EUR

recombinant Lab Reagents for Research





Promoted Lab polyclonals

Accu-Tell COVID-19 IgG/IgM Rapid Test

GEN-B352-20tests Accu test 20 tests 283.2 EUR

Accu-Tell COVID-19 IgG/IgM Rapid Test

GEN-B352-40tests Accu test 40 tests 385.2 EUR

2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma)

GEN-402-25tests All test 25 tests 292.8 EUR

Human TES(Testin) ELISA Kit

EH1738 FN Test 96T 681.12 EUR

T(Testosterone) ELISA Kit

EU0400 FN Test 96T 571.5 EUR

Rat T(Testosterone) ELISA Kit

ER1462 FN Test 96T 628.92 EUR

Rat Cholesterol ELISA ELISA

E01A11128 BlueGene 96T 700 EUR

Goat Cholesterol ELISA ELISA

E01A46041 BlueGene 96T 700 EUR

Mouse Cholesterol ELISA ELISA

E01A19869 BlueGene 96T 700 EUR

Human Cholesterol ELISA ELISA

E01A2368 BlueGene 96T 700 EUR

Sheep Cholesterol ELISA ELISA

E01A98335 BlueGene 96T 700 EUR

Monkey Cholesterol ELISA ELISA

E01A72187 BlueGene 96T 700 EUR

Canine Cholesterol ELISA ELISA

E01A63475 BlueGene 96T 700 EUR

Our used rec. in Pubmed.

CD11b Antibody Antibody

ABD2911 Lifescience Market 100 ug 525.6 EUR

Anti- GPR162 Antibody Antibody

GWB-39B7E0 GenWay Biotech 0.05 ml Ask for price

Anti- GPR162 Antibody Antibody

GWB-AAD3BE GenWay Biotech 0.05 ml Ask for price

Anti- GPR162 Antibody Antibody

GWB-C5010A GenWay Biotech 0.05 ml Ask for price

MAD1L1 antibody [9B10] Antibody

GWB-5C6547 GenWay Biotech 0.05 ml Ask for price

Thyroxine (T4) Antibody Antibody

GWB-DF4FFA GenWay Biotech 1 mg Ask for price

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.08ML NSJ Bioreagents 0.08 ml 140.25 EUR

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR

Tau (Ab-262) Antibody Antibody

E11-7239B EnoGene 100μg/100μl 225 EUR

MDR3 P-glycoprotein Antibody Mouse Monoclonal Antibody, Antibody

GWB-120022 GenWay Biotech 0.1 mg Ask for price

Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis

Regulator of ribosome synthesis 1 (RRS1) is a key factor in ribosome biosynthesis and other cellular functions. High level of RRS1 in breast cancer cell lines is associated with increased cell proliferation, invasion and migration. RRS1 controls the assembly of the 60s subunit and maturation of 25S rRNA during ribosome biosynthesis.
In this study, lentiviral transfection of sh‑RNA was used to knock down the level of RRS1, to detect the effect of RRS1 on cell function and to explore the specific mechanism of RRS1 affecting cell invasion and metastasis by COIP and dual‑luciferase reporter gene assays.
The present study found that RRS1 knockdown reduced the accumulation of ribosome protein L11 (RPL11) in the nucleolus, which then migrated to the nucleoplasm and bound to c‑Myc. This inhibited trans‑activation of SNAIL by c‑Myc and eventually decreased the invasion and metastasis capacity of the human breast cancer cell line BT549.
Taken together, RRS1 regulates invasion and metastasis of human breast cancer cells through the RPL11‑c‑Myc‑SNAIL axis. The findings are of great significance for exploring the mechanism of breast cancer invasion and metastasis and the corresponding regulatory factors.

Jumonji-C domain-containing protein 5 suppresses proliferation and aerobic glycolysis in pancreatic cancer cells in a cMyc-dependent manner

Despite the importance of metabolic reprogramming in cancer cells, the molecular mechanism regulating the tumor metabolic shift is still poorly understood. Deregulation of Jumonji-C domain-containing protein 5 (JMJD5) has been associated with multiple facets of biological processes in cancer cells.
However, the role of JMJD5 in pancreatic cancer cells has seldom been discussed and requires further investigation. In the present study, by silencing or overexpressing JMJD5 in pancreatic cancer cells, we examined the impact of JMJD5 on cell proliferation and glucose metabolism. Using a dual luciferase assay, we assessed the effect of JMJD5 on the transcriptional activity of the c-Myc target gene.
Analyzing The Cancer Genome Atlas and the Gene Expression Omnibus datasets revealed that low JMJD5 expression was associated with poor prognosis in patients with pancreatic cancer.
JMJD5 loss promoted pancreatic cancer cell proliferation and induced a cellular metabolic shift from oxidative phosphorylation to glycolysis. In addition, in vivo experiments confirmed that ectopic JMJD5 expression inhibited cancer cell growth and the expression of glycolytic enzymes, such as lactate dehydrogenase and phosphoglycerate kinase 1.
Moreover, JMJD5 negatively regulated c-Myc expression, the main regulator of cancer metabolism, leading to decreased c-Myc-targeted gene expression. Overall, the present study indicated that decreased JMJD5 expression promoted cell proliferation and glycolytic metabolism in pancreatic cancer cells in a c-Myc-dependent manner.

Imaging-Based Screening of Deubiquitinating Proteases Identifies Otubain-1 as a Stabilizer of cMYC

The ubiquitin-proteasome pathway precisely controls the turnover of transcription factors in the nucleus, playing an important role in maintaining appropriate quantities of these regulatory proteins. The transcription factor c-MYC is essential for normal development and is a critical cancer driver. Despite being highly expressed in several tissues and malignancies, the c-MYC protein is also continuously targeted by the ubiquitin-proteasome pathway, which can either facilitate or inhibit c-MYC degradation. Deubiquitinating proteases can remove ubiquitin chains from target proteins and rescue them from proteasomal digestion.
This study sought to determine novel elements of the ubiquitin-proteasome pathway that regulate c-MYC levels. We performed an overexpression screen with 41 human proteases to identify which deubiquitinases stabilize c-MYC. We discovered that the highly expressed Otubain-1 (OTUB1) protease increases c-MYC protein levels.
Confirming its role in enhancing c-MYC activity, we found that elevated OTUB1 correlates with inferior clinical outcomes in the c-MYC-dependent cancer multiple myeloma, and overexpression of OTUB1 accelerates the growth of myeloma cells. In summary, our study identifies OTUB1 as a novel amplifier of the proto-oncogene c-MYC.

Rational design of small-molecules to recognize G-quadruplexes of cMYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer

DNA G4-structures from human c-MYC promoter and telomere are considered as important drug targets; however, the developing of small-molecule-based fluorescent binding ligands that are highly selective in targeting these G4-structures over other types of nucleic acids is challenging.
We herein report a new approach of designing small molecules based on a non-selective thiazole orange scaffold to provide two-directional and multi-site interactions with flanking residues and loops of the G4-motif for better selectivity.
The ligands are designed to establish multi-site interactions in the G4-binding pocket. This structural feature may render the molecules higher selectivity toward c-MYC G4s than other structures.
The ligand-G4 interaction studied with 1H NMR may suggest a stacking interaction with the terminal G-tetrad. Moreover, the intracellular co-localization study with BG4 and cellular competition experiments with BRACO-19 may suggest that the binding targets of the ligands in cells are most probably G4-structures.
Furthermore, the ligands that either preferentially bind to c-MYC promoter or telomeric G4s are able to downregulate markedly the c-MYC and hTERT gene expression in MCF-7 cells, and induce senescence and DNA damage to cancer cells. The in vivo antitumor activity of the ligands in MCF-7 tumor-bearing mice is also demonstrated.

cMyc Targets HDAC3 to Suppress NKG2DL Expression and Innate Immune Response in N-Type SCLC through Histone Deacetylation

SCLC is an aggressive malignancy with a very poor prognosis and limited effective therapeutic options. Despite the high tumor mutational burden, responses to immunotherapy are rare in SCLC patients, which may be due to the lack of immune surveillance.
Here, we aimed to examine the role and mechanism of oncogene MYC in the regulation of NKG2DL, the most relevant NK-activating ligand in SCLC-N.
Western Blotting, Immunofluorescence, flow cytometry, quantitative real-time PCR (qRT-PCR), Co-Immunoprecipitation (Co-IP), chromatin immunoprecipitation (ChIP), and Cytotoxicity assay were used on H2227 cells, H446 cells, and other SCLC cell lines, and we found that c-Myc negatively regulated NKG2DL expression in SCLC-N cells. Mechanistically, c-Myc recruited HDAC3 to deacetylate H3K9ac at the promoter regions of MICA and MICB, suppressing the MICA/B expression of SCLC-N cells and the cytotoxicity of NK cells.

Myc-Tag (c-myc, myc-1 epitope tag)

MBS6507981-01mL MyBiosource 0.1mL 660 EUR

Myc-Tag (c-myc, myc-1 epitope tag)

MBS6507981-5x01mL MyBiosource 5x0.1mL 2810 EUR

Myc-Tag (c-myc, myc-1 epitope tag)

MBS6507983-01mL MyBiosource 0.1mL 660 EUR

Myc-Tag (c-myc, myc-1 epitope tag)

MBS6507983-5x01mL MyBiosource 5x0.1mL 2810 EUR

c-Myc Epitope (Myc) Antibody

20-abx130438 Abbexa
  • Ask for price
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

c-Myc Epitope (Myc) Antibody

20-abx132269 Abbexa
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

c-Myc Epitope (Myc) Antibody

abx132269-100tests Abbexa 100 tests 850 EUR

c-Myc Epitope (Myc) Antibody

abx130438-100l Abbexa 100 µl 850 EUR

c-Myc Epitope (Myc) Antibody

abx130438-1ml Abbexa 1 ml Ask for price

c-Myc Epitope (Myc) Antibody

abx130438-200l Abbexa 200 µl Ask for price

pMXs- c- Myc

PVT10447 Nova Lifetech 2ug 215 EUR

pCMV- Myc- C

PVT10696 Nova Lifetech 2ug 215 EUR

c Myc antibody

10R-8403 Fitzgerald 100 ul 471.6 EUR

c Myc antibody

MBS833287-INQUIRE MyBiosource INQUIRE Ask for price

Myc-Tag (c-myc, myc-1 epitope tag) (AP)

MBS6124726-01mL MyBiosource 0.1(mL 950 EUR

Myc-Tag (c-myc, myc-1 epitope tag) (AP)

MBS6124726-5x01mL MyBiosource 5x0.1mL 4115 EUR

Myc-Tag (c-myc, myc-1 epitope tag) (PE)

MBS6125894-01mL MyBiosource 0.1(mL 950 EUR
Treatment with selective HDAC3 inhibitor up-regulated the expression of NKG2DL on SCLC-N cells and increased the cytotoxicity of NK cells. Furthermore, analysis of the CCLE and Kaplan-Meier plotter data performed the negative correlation between MYC and NKG2DL in SCLC-N cells and the correlation with the prognosis of lung cancer patients.
Collectively, the results provided the new insight into the role and mechanism of c-Myc/HDAC3 axis in NKG2DL expression and innate immune escape of SCLC-N, suggesting the potential target for SCLC-N immunotherapy.