A significant proportion of couples at reproductive age rely on assisted reproductive technology to overcome infertility. In vitro fertilisation (IVF) involves typically the use of exogenous gonadotropins to stimulate the ovary to produce oocytes, which are collected surgically.

After fertilization by conventional IVF or intracytoplasmic sperm injection (ICSI), embryos are cultured in the embryology laboratory for a few days before being replaced into the uterus (fresh embryo transfer). Spare embryos can be vitrified and stored in liquid nitrogen to be transferred in a subsequent cycle.

Over the years, concerns have arisen about possible adverse outcomes of transferring embryos back to the uterus immediately after controlled ovarian stimulation (COS) as regards to obstetrical and perinatal outcomes. It has been suggested that high levels of hormone during COS could create a relatively hostile environment for embryo implantation whilst increasing the risk of ovarian hyperstimulation syndrome (OHSS).

With the remarkedly improvement of vitrification as an alternative to the slow-freezing technique for human embryos, a new strategy the so-called “freeze-all” (FA) or “elective frozen embryo transfer” (eFET) was introduced. This approach involves COS, followed by the elective cryopreservation of the entire cohort of viable embryos to be transferred to the uterus in subsequent cycles in a possibly more physiological environment, thus avoiding the supra-physiologic hormonal levels observed during COS.

The initial reports suggested that this policy could lead to improved pregnancy rates and reduced perinatal complications, which resulted in a steady increase and widespread use of FA globally. However, as data accumulated, it became clear that the use of FA to unselected couples undergoing ART offered no additional benefits over the conventional approach.

anti-ALP

YF-PA18461 50 ul
EUR 363
Description: Mouse polyclonal to ALP

ALP-B/ Rat ALP- B ELISA Kit

ELA-E0473r 96 Tests
EUR 886

Streptavidin Protein (ALP)

abx061009-2ml 2 ml
EUR 704

ALP Blocking Peptide

20-abx161265
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

ALP Blocking Peptide

DF12525-BP 1mg
EUR 195

Sheep ALP ELISA Kit

ESA0038 96Tests
EUR 521

Mouse ALP ELISA Kit

EMA0038 96Tests
EUR 521

Monkey ALP ELISA Kit

EMKA0038 96Tests
EUR 521

Porcine ALP ELISA Kit

EPA0038 96Tests
EUR 521

Rat ALP ELISA Kit

ERA0038 96Tests
EUR 521

Rabbit ALP ELISA Kit

ERTA0038 96Tests
EUR 521

Anserini ALP ELISA Kit

EAA0038 96Tests
EUR 521

Goat ALP ELISA Kit

EGTA0038 96Tests
EUR 521

Canine ALP ELISA Kit

ECA0038 96Tests
EUR 521

Chicken ALP ELISA Kit

ECKA0038 96Tests
EUR 521

Human ALP ELISA Kit

EHA0038 96Tests
EUR 521

Bovine ALP ELISA Kit

EBA0038 96Tests
EUR 521

Alkaline Phosphatase (ALP) Antibody

20-abx121265
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Alkaline Phosphatase (ALP) Antibody

abx038456-100ug 100 ug
EUR 391

Protein A Antibody (ALP)

abx023329-2ml 2 ml
EUR 843

Endoplasmin (GRP94) Antibody (ALP)

abx442250-200ug 200 ug
EUR 578

GRP75 (Grp75) Antibody (ALP)

abx442270-100ug 100 ug
EUR 565

ubiquitin (Ubiquitin) Antibody (ALP)

abx442291-200ug 200 ug
EUR 620

ubiquitin (Ubiquitin) Antibody (ALP)

abx442300-200ug 200 ug
EUR 620

Rhodopsin (RHO) Antibody (ALP)

abx442303-100ug 100 ug
EUR 578

Rhodopsin (RHO) Antibody (ALP)

abx442304-100ug 100 ug
EUR 578

Synaptophysin (SYP) Antibody (ALP)

abx442305-100ug 100 ug
EUR 509

Syntaxin (STX) Antibody (ALP)

abx442308-100ug 100 ug
EUR 537

Piccolo (Pclo) Antibody (ALP)

abx442314-100ug 100 ug
EUR 565

Kir2.1 (Kir2.1) Antibody (ALP)

abx442362-100ug 100 ug
EUR 578

Kir2.2 (Kir2.2) Antibody (ALP)

abx442363-100ug 100 ug
EUR 578

VGLUT1 (VGLUT1) Antibody (ALP)

abx442402-100ug 100 ug
EUR 578

VGLUT2 (VGLUT2) Antibody (ALP)

abx442403-100ug 100 ug
EUR 578

Versican (VCAN) Antibody (ALP)

abx442447-100ug 100 ug
EUR 578

Malin (NHLRC1) Antibody (ALP)

abx442452-100ug 100 ug
EUR 578

Laforin (EPM2A) Antibody (ALP)

abx442472-100ug 100 ug
EUR 578

Kir6.1 (Kir6.1) Antibody (ALP)

abx442497-100ug 100 ug
EUR 578

Citrulline (CIT) Antibody (ALP)

abx442502-100ug 100 ug
EUR 662

Citrulline (CIT) Antibody (ALP)

abx442503-100ug 100 ug
EUR 662

Endoplasmin (GRP94) Antibody (ALP)

abx447036-100ug 100 ug
EUR 537

Piccolo (Pclo) Antibody (ALP)

abx447495-100ug 100 ug
EUR 578

ubiquitin (Ubiquitin) Antibody (ALP)

abx447954-200ul 200 ul
EUR 620

Metallothionein (mymT) Antibody (ALP)

abx448218-100ug 100 ug
EUR 578

ubiquitin (Ubiquitin) Antibody (ALP)

abx444810-100ug 100 ug
EUR 398

Calreticulin (CALR) Antibody (ALP)

abx445319-200ul 200 ul
EUR 551

Bassoon (BSN) Antibody (ALP)

abx446594-100ug 100 ug
EUR 578

Rubicon (Rubicon) Antibody (ALP)

abx446730-100ug 100 ug
EUR 578

Alkaline Phosphatase (ALP) Antibody

20-abx175316
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug

Alkaline Phosphatase (ALP) Antibody

20-abx175317
  • EUR 1247.00
  • EUR 592.00
  • 1 mg
  • 200 ug

Anti-ASRGL1 / ALP antibody

STJ71356 100 µg
EUR 359

Recombinant Alkaline Phosphatase (ALP)

4-RPB472Bo01
  • EUR 503.20
  • EUR 238.00
  • EUR 1612.00
  • EUR 604.00
  • EUR 1108.00
  • EUR 400.00
  • EUR 3880.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Bovine Alkaline Phosphatase expressed in: E.coli

ALP ELISA KIT|Human

EF009206 96 Tests
EUR 689

QuantiFluo ALP Detection Reagent

QFALP-6mL 600
EUR 156
Description: A stable 4-methylumbelliferyl phosphate (MUP) liquid substrate reagent formulated for detecting alkaline phosphatase ALP, e.g. in ELISA. This single reagent produces a highly fluorescent product (360/450 nm) when dephosphorylated by ALP. The fluorescent p

XTT CELL VIABILITY ASSAY KIT (1000 ASSAY)

30007 1KIT
EUR 236
Description: Minimum order quantity: 1 unit of 1KIT

Human Phosphatase (ALP) CLIA Kit

20-abx496324
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse ALP-B ELISA Kit

EMA0794 96Tests
EUR 521

Porcine ALP-B ELISA Kit

EPA0794 96Tests
EUR 521

Rat ALP-B ELISA Kit

ERA0794 96Tests
EUR 521

Rabbit ALP-B ELISA Kit

ERTA0794 96Tests
EUR 521

Anserini ALP-B ELISA Kit

EAA0794 96Tests
EUR 521

Guinea Pig ALP ELISA Kit

EGA0038 96Tests
EUR 521

Goat ALP-B ELISA Kit

EGTA0794 96Tests
EUR 521

Canine ALP-B ELISA Kit

ECA0794 96Tests
EUR 521

Human ALP-B ELISA Kit

EHA0794 96Tests
EUR 521

Bovine ALP-B ELISA Kit

EBA0794 96Tests
EUR 521

Human Alkaline Phosphatase (ALP) Enzyme

abx077002-100U 100 U
EUR 565

Fluorescein Isothiocyanate (FITC) Antibody (ALP)

abx022679-1ml 1 ml
EUR 718

Alkaline Phosphatase(ALP/597) Antibody

BNCA0597-250 250uL
EUR 383
Description: Primary antibody against Alkaline Phosphatase(ALP/597), APC conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCAP0597-100 100uL
EUR 199
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCAP0597-500 500uL
EUR 544
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC810597-100 100uL
EUR 199
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF680R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC810597-500 500uL
EUR 544
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF680R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC880597-100 100uL
EUR 199
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF488A conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC880597-500 500uL
EUR 544
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF488A conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCB0597-100 100uL
EUR 199
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Biotin conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCB0597-500 500uL
EUR 544
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Biotin conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC550597-100 100uL
EUR 199
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF555 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC550597-500 500uL
EUR 544
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF555 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC430597-100 100uL
EUR 199
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF543 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC430597-500 500uL
EUR 544
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF543 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC470597-100 100uL
EUR 199
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF647 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC470597-500 500uL
EUR 544
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF647 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC940597-100 100uL
EUR 199
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF594 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC940597-500 500uL
EUR 544
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF594 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCP0597-250 250uL
EUR 383
Description: Primary antibody against Alkaline Phosphatase(ALP/597), PerCP conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC040597-100 100uL
EUR 199
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF405S conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC040597-500 500uL
EUR 544
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF405S conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC050597-100 100uL
EUR 199
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF405M conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC050597-500 500uL
EUR 544
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF405M conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase (ALP) Antibody Pair

20-abx370189
  • EUR 1261.00
  • EUR 829.00
  • 10 × 96 tests
  • 5 × 96 tests

Alkaline Phosphatase (ALP) Antibody (HRP)

abx411095-1ml 1 ml
EUR 453

Ankyrin B (ANKB) Antibody (ALP)

abx442408-100ug 100 ug
EUR 578

Ankyrin G (ANK3) Antibody (ALP)

abx442412-100ug 100 ug
EUR 578

Ankyrin-B (ANK2) Antibody (ALP)

abx442422-100ug 100 ug
EUR 578

Endoribonuclease Dicer (Dicer) Antibody (ALP)

abx442424-100ug 100 ug
EUR 578

Pannexin 2 (Panx2) Antibody (ALP)

abx442428-100ug 100 ug
EUR 578

Synaptotagmin-10 (Syt10) Antibody (ALP)

abx442431-100ug 100 ug
EUR 578

Synaptotagmin-7 (Syt7) Antibody (ALP)

abx442432-100ug 100 ug
EUR 578

Nonetheless, current evidence based on randomized controlled trials and observational studies indicates that FA might be justified in selected clinical scenarios, such as those involving the risk of OHSS. By contrast, there is a lack of evidence to support the FA policy for other indications, such as implantation failure or high progesterone levels on the trigger day. This review summarizes the clinical effectiveness of FA with the main focus on the health of offspring.