Primordial germ cells (PGCs) are the founder cells of the germline. Via gametogenesis and fertilisation this lineage generates a brand new embryo in the subsequent technology. PGCs are additionally the cell of origin of multilineage teratocarcinomas.
In vitro, mouse PGCs can provide rise to embryonic germ (EG) cells – pluripotent stem cells that may contribute to main chimaeras when launched into pre-implantation embryos. Thus, PGCs can provide rise to pluripotent cells in the course of the developmental cycle, throughout teratocarcinogenesis and by in vitro tradition. However, there isn’t any proof that PGCs can differentiate instantly into somatic cell varieties.
Furthermore, it’s typically assumed that PGCs don’t contribute to chimaeras following injection into the early mouse embryo. However, these knowledge have by no means been formally revealed. Here, we current the main knowledge from the unique PGC-injection experiments carried out 40 years in the past, alongside outcomes from newer research in three separate laboratories.
These outcomes have knowledgeable and influenced present fashions of the relationship between pluripotency and the germline cycle. Current applied sciences enable additional experiments to substantiate and develop upon these findings and permit definitive conclusions as to the developmental efficiency of PGCs.

On the fate of primordial germ cells injected into early mouse embryos.
MC Chang–Reproductive biologist of distinction 1908-1991.
This article evaluations the outstanding life and main scientific achievements of the reproductive biologist M.C. Chang. His scholarly profession progressed from college in Peking, through Edinburgh, Scotland, and Cambridge, England, to the newly based Worcester Foundation for Experimental Biology in Massachusetts. At every stage, the hand of fate is famous as are the help and encouragement of key professors.
Chang’s personal contributions on capacitation of spermatozoa, in vitro fertilisation of mammalian eggs, and transplantation of oocytes and embryos are all introduced out, as is his important enter to the creation and improvement of a steroid contraceptive capsule.
TCR alpha / beta Antibody |
abx140255-01mg |
Abbexa |
0.1 mg |
EUR 376.8 |
|
alpha beta TcR antibody (biotin) |
61R-1695 |
Fitzgerald |
100 ug |
EUR 379.2 |
Description: Mouse monoclonal alpha beta TcR antibody (biotin) |
TCR alpha / beta Antibody (PE) |
abx139897-100tests |
Abbexa |
100 tests |
EUR 577.2 |
|
TCR alpha / beta Antibody (PE) |
abx140308-01mg |
Abbexa |
0.1 mg |
EUR 510 |
|
TCR alpha / beta Antibody (APC) |
abx139898-100tests |
Abbexa |
100 tests |
EUR 577.2 |
|
TCR alpha / beta Antibody (FITC) |
abx139900-100tests |
Abbexa |
100 tests |
EUR 510 |
|
TCR alpha / beta Antibody (FITC) |
abx140307-01mg |
Abbexa |
0.1 mg |
EUR 477.6 |
|
TCR alpha / beta Antibody (PerCP) |
abx139896-100tests |
Abbexa |
100 tests |
EUR 577.2 |
|
TCR alpha / beta Antibody (Biotin) |
abx139899-01mg |
Abbexa |
0.1 mg |
EUR 510 |
|
T-Cell Receptor Alpha Beta (TCR Alpha/Beta) Antibody |
abx414734-05mg |
Abbexa |
0.5 mg |
EUR 994.8 |
|
T-Cell Receptor Alpha Beta (TCR Alpha/Beta) Antibody |
abx414736-025mg |
Abbexa |
0.25 mg |
EUR 678 |
|
T-Cell Receptor Alpha Beta (TCR Alpha/Beta) Antibody |
abx414737-01mg |
Abbexa |
0.1 mg |
EUR 526.8 |
|
T-Cell Receptor Alpha Beta (TCR Alpha/Beta) Antibody |
abx413042-025mg |
Abbexa |
0.25 mg |
EUR 678 |
|
Anti-Hu TCR alpha/beta PE |
1P-607-T025 |
ExBio |
25 tests |
EUR 168 |
Anti-Hu TCR alpha/beta PE |
1P-607-T100 |
ExBio |
100 tests |
EUR 288 |
Anti-Rt TCR alpha/beta PE |
1P-653-C025 |
ExBio |
0.025 mg |
EUR 146.4 |
Anti-Rt TCR alpha/beta PE |
1P-653-C100 |
ExBio |
0.1 mg |
EUR 244.8 |
Anti-Hu TCR alpha/beta APC |
1A-607-T025 |
ExBio |
25 tests |
EUR 168 |
Anti-Hu TCR alpha/beta APC |
1A-607-T100 |
ExBio |
100 tests |
EUR 288 |
Anti-Hu TCR alpha/beta FITC |
1F-607-T025 |
ExBio |
25 tests |
EUR 146.4 |
Anti-Hu TCR alpha/beta FITC |
1F-607-T100 |
ExBio |
100 tests |
EUR 244.8 |
Anti-Rt TCR alpha/beta FITC |
1F-653-C025 |
ExBio |
0.025 mg |
EUR 135.6 |
Anti-Rt TCR alpha/beta FITC |
1F-653-C100 |
ExBio |
0.1 mg |
EUR 223.2 |
Anti-Hu TCR alpha/beta PerCP |
PC-607-T025 |
ExBio |
25 tests |
EUR 168 |
Anti-Hu TCR alpha/beta PerCP |
PC-607-T100 |
ExBio |
100 tests |
EUR 288 |
Anti-Hu TCR alpha/beta Biotin |
1B-607-C025 |
ExBio |
0.025 mg |
EUR 146.4 |
Anti-Hu TCR alpha/beta Biotin |
1B-607-C100 |
ExBio |
0.1 mg |
EUR 244.8 |
T-Cell Receptor Alpha Beta (TCR Alpha/Beta) Antibody (FITC) |
abx414735-01mg |
Abbexa |
0.1 mg |
EUR 610.8 |
|
T-Cell Receptor Alpha Beta (TCR Alpha/Beta) Antibody (FITC) |
abx413043-01mg |
Abbexa |
0.1 mg |
EUR 610.8 |
|
T-Cell Receptor Alpha Beta (TCR Alpha/Beta) Antibody (FITC) |
abx413044-05mg |
Abbexa |
0.5 mg |
EUR 861.6 |
|
Anti-Hu TCR alpha/beta Purified |
11-607-C025 |
ExBio |
0.025 mg |
EUR 118.8 |
Anti-Hu TCR alpha/beta Purified |
11-607-C100 |
ExBio |
0.1 mg |
EUR 189.6 |
Anti-Rt TCR alpha/beta Purified |
11-653-C100 |
ExBio |
0.1 mg |
EUR 157.2 |
T-Cell Receptor Alpha Beta V Beta 1 (TCR Alpha/Beta Vb1) Antibody |
abx415177-025mg |
Abbexa |
0.25 mg |
EUR 710.4 |
|
T-Cell Receptor Alpha Beta V Beta 2 (TCR Alpha/Beta Vb2) Antibody |
abx415178-025mg |
Abbexa |
0.25 mg |
EUR 710.4 |
|
Rabbit Anti-Human p73 alpha/beta antiserum # 1 |
P73A11-S |
Alpha Diagnostics |
100 ul |
EUR 548.4 |
Human p73 alpha/beta Control/blocking peptide #1 |
P73A11-P |
Alpha Diagnostics |
100 ug |
EUR 196.8 |
Alpha V Beta 5 Integrin, Peptide Aptamer, unlabeled |
AP-301-U |
Alpha Diagnostics |
5 mg |
Ask for price |
Actin (Pan, alpha, beta, gamma) Control/blocking peptide |
ACTB22-P |
Alpha Diagnostics |
100 ug |
EUR 196.8 |
Alpha V Beta 5 Integrin, Peptide Aptamer, Biotinylated |
AP-301-B |
Alpha Diagnostics |
1 mg |
Ask for price |
Rabbit Anti-Human p73 alpha/beta IgG # 1, aff pure |
P73A11-A |
Alpha Diagnostics |
100 ug |
EUR 578.4 |
Alpha V Beta 5 Integrin, Peptide Aptamer, FITC labelled |
AP-301-F |
Alpha Diagnostics |
1 mg |
Ask for price |
Rabbit Anti-Actin (Pan, alpha, beta, gamma) IgG, aff pure |
ACTB22-A |
Alpha Diagnostics |
100 ug |
EUR 578.4 |
Mouse Monoclonal Anti-Actin (Pan, alpha, beta, gamma)-biotinylated |
ACTB24-BTN |
Alpha Diagnostics |
50 ul |
EUR 489.6 |
Mouse Monoclonal Anti-Actin (Pan, alpha, beta, gamma) IgG, aff pure |
ACTB24-M |
Alpha Diagnostics |
100 ug |
EUR 578.4 |
Monoclonal Anti-Human/mouse/rat HSP90 alpha/beta IgG, aff pure |
HSP901-M |
Alpha Diagnostics |
100 ul |
EUR 578.4 |
Mouse Monoclonal Anti-Actin (Pan, alpha, beta, gamma) IgG-Cy3 conjugate |
ACTB24-Cy3 |
Alpha Diagnostics |
100 ul |
EUR 489.6 |
Mouse Monoclonal Anti-Actin (Pan, alpha, beta, gamma) IgG-FITC conjugate |
ACTB24-FITC |
Alpha Diagnostics |
100 ul |
EUR 489.6 |
TCR alpha antibody |
20R-1837 |
Fitzgerald |
100 ug |
EUR 807.6 |
Description: Rabbit polyclonal TCR alpha antibody |
TCR alpha Antibody |
5648-100 |
Biovision |
each |
EUR 424.8 |
TCR alpha Antibody |
5648-30T |
Biovision |
each |
EUR 175.2 |
TCR alpha antibody |
70R-12400 |
Fitzgerald |
100 ug |
EUR 552 |
Description: Rabbit polyclonal TCR alpha antibody |
Endothelial intergerin Alpha-V Beta-3 (Clone 17.16), RNA Aptamer, unlabeled |
AR-287-U |
Alpha Diagnostics |
Custom |
Ask for price |
Pig Anti-C. perfringens toxins (Alpha+beta+Epsilon) Antibody ELISA, 96 tests, Quantitative |
RB-500720-1 |
Alpha Diagnostics |
100 ul |
EUR 854.4 |
Dog Anti-C. perfringens toxins (Alpha+beta+Epsilon) Antibody ELISA, 96 tests, Quantitative |
RB-500760-1 |
Alpha Diagnostics |
100 ul |
EUR 854.4 |
Mouse Anti-C. perfringens toxins (Alpha+beta+Epsilon) Antibody ELISA, 96 tests, Quantitative |
RB-500710-1 |
Alpha Diagnostics |
100 ul |
EUR 854.4 |
Rabbit Anti-C. perfringens toxins (Alpha+beta+Epsilon) Antibody ELISA, 96 tests, Quantitative |
RB-500700-1 |
Alpha Diagnostics |
100 ul |
EUR 854.4 |
Chicken Anti-C. perfringens toxins (Alpha+beta+Epsilon) Antibody ELISA, 96 tests, Quantitative |
RB-500750-1 |
Alpha Diagnostics |
100 ul |
EUR 854.4 |
Goat/Sheep Anti-C. perfringens toxins (Alpha+beta+Epsilon) Antibody ELISA, 96 tests, Quantitative |
RB-500730-1 |
Alpha Diagnostics |
100 ul |
EUR 854.4 |
Cow/Bovine Anti-C. perfringens toxins (Alpha+beta+Epsilon) Antibody ELISA, 96 tests, Quantitative |
RB-500740-1 |
Alpha Diagnostics |
100 ul |
EUR 854.4 |
TRAC Antibody / TCR alpha |
RQ4617 |
NSJ Bioreagents |
100ug |
EUR 356.15 |
Description: T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. |
TCR beta Antibody |
20-abx201040 |
Abbexa |
|
|
|
TCR beta Antibody |
20-abx218918 |
Abbexa |
|
|
|
TCR beta antibody |
10R-6585 |
Fitzgerald |
100 ug |
EUR 217.2 |
Description: Armenian Hamster monoclonal TCR beta antibody |
TCR beta antibody |
20R-1838 |
Fitzgerald |
100 ug |
EUR 807.6 |
Description: Rabbit polyclonal TCR beta antibody |
TCR beta Antibody |
5651-100 |
Biovision |
each |
EUR 392.4 |
TCR beta Antibody |
5651-30T |
Biovision |
each |
EUR 175.2 |
TCR beta antibody |
70R-12401 |
Fitzgerald |
100 ug |
EUR 501.6 |
Description: Rabbit polyclonal TCR beta antibody |
TCR alpha Blocking Peptide |
5648BP-50 |
Biovision |
each |
EUR 183.6 |
TCR alpha Blocking Peptide |
33R-10580 |
Fitzgerald |
50 ug |
EUR 418.8 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of TCR alpha antibody, catalog no. 20R-1837 |
TCR alpha Blocking Peptide |
33R-11053 |
Fitzgerald |
50 ug |
EUR 229.2 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of TCR alpha antibody, catalog no. 70R-12400 |
Polyclonal TCR alpha Antibody |
AMM08788G |
Leading Biology |
0.1mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TCR alpha . This antibody is tested and proven to work in the following applications: |
Mouse alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like (MGAT4D) Control/blocking peptide |
AB-23037-P |
Alpha Diagnostics |
100ug |
EUR 196.8 |
V alpha 24 J alpha 18 TCR antibody |
10R-6544 |
Fitzgerald |
100 ug |
EUR 308.4 |
Description: Mouse monoclonal V alpha 24 J alpha 18 TCR antibody |
TCR beta Antibody (PE) |
20-abx201037 |
Abbexa |
|
|
|
TCR beta antibody (PE) |
61R-1386 |
Fitzgerald |
100 ug |
EUR 262.8 |
Description: Armenian Hamster monoclonal TCR beta antibody (PE) |
Rabbit Anti-Mouse alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like (MGAT4D) IgG (aff pure) |
AB-23037-A |
Alpha Diagnostics |
100ug |
EUR 578.4 |
TCR beta Antibody (APC) |
20-abx201033 |
Abbexa |
|
|
|
TCR beta Antibody (FITC) |
20-abx201036 |
Abbexa |
-
EUR 343.20
-
EUR 292.80
-
EUR 477.60
|
|
|
TCR beta antibody (FITC) |
61R-1156 |
Fitzgerald |
100 ug |
EUR 217.2 |
Description: Armenian Hamster monoclonal TCR beta antibody (FITC) |
TCR beta Antibody (PerCP) |
20-abx201038 |
Abbexa |
|
|
|
TCR beta Antibody (Biotin) |
20-abx201034 |
Abbexa |
|
|
|
TCR beta antibody (biotin) |
61R-1632 |
Fitzgerald |
100 ug |
EUR 198 |
Description: Armenian Hamster monoclonal TCR beta antibody (biotin) |
V alpha 2 TCR antibody (PE) |
61R-1356 |
Fitzgerald |
100 ug |
EUR 379.2 |
Description: Rat monoclonal V alpha 2 TCR antibody (PE) |
TCR beta Blocking Peptide |
5651BP-50 |
Biovision |
each |
EUR 183.6 |
TCR beta Blocking Peptide |
33R-10581 |
Fitzgerald |
50 ug |
EUR 418.8 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of TCR beta antibody, catalog no. 20R-1838 |
TCR beta Blocking Peptide |
33R-11054 |
Fitzgerald |
50 ug |
EUR 229.2 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of TCR beta antibody, catalog no. 70R-12401 |
TCR beta Blocking Peptide |
DF8621-BP |
Affbiotech |
1mg |
EUR 234 |
V alpha 24 J alpha 18 TCR antibody (PE) |
61R-1353 |
Fitzgerald |
100 tests |
EUR 664.8 |
Description: Mouse monoclonal V alpha 24 J alpha 18 TCR antibody (PE) |
V alpha 2 TCR antibody (FITC) |
61R-1145 |
Fitzgerald |
100 ug |
EUR 340.8 |
Description: Rat monoclonal V alpha 2 TCR antibody (FITC) |
Human Anti-Parietal cell (alpha and beta subunits of the Parietal Cell (H//K/ATPase) IgG ELISA kit, 96 tests, Quantitative |
3300-315-PRG |
Alpha Diagnostics |
1 kit |
EUR 708 |
Polyclonal TCR beta Antibody |
APR00309G |
Leading Biology |
0.1mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TCR beta . This antibody is tested and proven to work in the following applications: |
TCR Beta Polyclonal Antibody |
ABP52577-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of TCR Beta from Human. This TCR Beta antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TCR ? |
TCR Beta Polyclonal Antibody |
ABP52577-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of TCR Beta from Human. This TCR Beta antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TCR ? |
TCR Beta Polyclonal Antibody |
ABP52577-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of TCR Beta from Human. This TCR Beta antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TCR ? |
V alpha 2 TCR antibody (biotin) |
61R-1598 |
Fitzgerald |
100 ug |
EUR 249.6 |
Description: Rat monoclonal V alpha 2 TCR antibody (biotin) |
TCR beta antibody (allophycocyanin) |
61R-1895 |
Fitzgerald |
100 ug |
EUR 418.8 |
Description: Armenian Hamster monoclonal TCR beta antibody (allophycocyanin) |
TCR beta (V beta 5.3-related) Antibody |
abx140251-01mg |
Abbexa |
0.1 mg |
EUR 477.6 |
|
TCR beta (V beta 5.3-related) Antibody |
abx140264-01mg |
Abbexa |
0.1 mg |
EUR 477.6 |
|
Recombinant (E.Coli) Human p38 alpha/SAPK2 alpha |
RP-675 |
Alpha Diagnostics |
1 ug |
EUR 343.2 |
V alpha 2 TCR antibody (allophycocyanin) |
61R-1776 |
Fitzgerald |
100 ug |
EUR 573.6 |
Description: Rat monoclonal V alpha 2 TCR antibody (allophycocyanin) |
TCR beta Antibody (CF-Blue) |
20-abx201035 |
Abbexa |
|
|
|
Anti-Ms TCR beta Purified |
11-571-C100 |
ExBio |
0.1 mg |
EUR 135.6 |
V beta 13.2 TCR antibody (PE) |
61R-1349 |
Fitzgerald |
100 tests |
EUR 522 |
Description: Mouse monoclonal V beta 13.2 TCR antibody (PE) |
TCR beta Antibody (PerCP-Cy5.5) |
20-abx201039 |
Abbexa |
|
|
|
anti-TCR alpha |
YF-PA14966 |
Abfrontier |
50 ug |
EUR 435.6 |
Description: Mouse polyclonal to TCR alpha |
anti-TCR alpha |
YF-PA14967 |
Abfrontier |
50 ul |
EUR 435.6 |
Description: Mouse polyclonal to TCR alpha |
V beta 13.1 TCR antibody (FITC) |
61R-1141 |
Fitzgerald |
25 tests |
EUR 282 |
Description: Mouse monoclonal V beta 13.1 TCR antibody (FITC) |
human Topoisomerase II alpha (TOP2 alpha) Control/blocking peptide |
TOP2A11-P |
Alpha Diagnostics |
100 ug |
EUR 196.8 |
V beta 10b TCR antibody (PE) |
61R-1352 |
Fitzgerald |
100 ug |
EUR 379.2 |
Description: Rat monoclonal V beta 10b TCR antibody (PE) |
Recombinant purified, human Interleukin-1 alpha (IL-1 alpha), active |
IL1A15-R-10 |
Alpha Diagnostics |
10 ug |
EUR 416.4 |
Rabbit Anti-human Topoisomerase II alpha (TOP2 alpha) IgG, aff pure |
TOP2A11-A |
Alpha Diagnostics |
100 ug |
EUR 578.4 |
TCR beta (V beta 5.3-related) Antibody (Azide free) |
abx140265-01mg |
Abbexa |
0.1 mg |
EUR 477.6 |
|
Anti-TCR alpha (4H8) |
YF-MA15787 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to TCR alpha |
AP2 alpha/beta Antibody |
AF0535 |
Affbiotech |
200ul |
EUR 420 |
IKK alpha/ beta Antibody |
AF6013 |
Affbiotech |
200ul |
EUR 420 |
IKK alpha/ beta Antibody |
AF6014 |
Affbiotech |
200ul |
EUR 420 |
IKK alpha/ beta Antibody |
AF6800 |
Affbiotech |
100ul |
EUR 420 |
IKK alpha/beta antibody |
70R-31307 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal IKK alpha/beta antibody |
IKK alpha/beta antibody |
70R-49555 |
Fitzgerald |
100 ul |
EUR 344.4 |
Description: Purified Polyclonal IKK alpha/beta antibody |
AP2 alpha/beta antibody |
70R-50465 |
Fitzgerald |
100 ul |
EUR 292.8 |
Description: Purified Polyclonal AP2 alpha/beta antibody |
AP2 alpha / beta Antibody |
20-abx008651 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
IKK Antibody (alpha/beta) |
F47192-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
Description: IKKA is a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. |
IKK Antibody (alpha/beta) |
F47192-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
Description: IKKA is a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. |
IKK alpha/beta Antibody |
RQ4722 |
NSJ Bioreagents |
100ul |
EUR 356.15 |
Description: The IkappaB kinase complex is composed of three subunits each encoded by a separate gene: IKK alpha (also known as IKK1 and CHUK), IKK beta (also known as IKK2 and IKBKB), and IKK gamma (also known as NEMO/ and IKBKG). The alpha- and beta- subunits together are catalytically active whereas the gamma-subunit serves a regulatory function. The IKKa and IKKb kinase subunits are homologous in structure, composed of a kinase domain, as well as leucine zipper and helix-loop-helix dimerization domains, and a carboxy-terminal NEMO-binding domain (NBD). [Wiki] |
PP2A alpha/beta antibody |
10R-8502 |
Fitzgerald |
100 ul |
EUR 471.6 |
Description: Mouse monoclonal PP2A alpha/beta antibody |
PP2A alpha/beta antibody |
10R-8503 |
Fitzgerald |
100 ul |
EUR 471.6 |
Description: Mouse monoclonal PP2A alpha/beta antibody |
GSK3 alpha/beta Antibody |
29039-100ul |
SAB |
100ul |
EUR 302.4 |
GSK3 alpha/beta antibody |
70R-30578 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal GSK3 alpha/beta antibody |
GSK3 alpha/ beta Antibody |
AF6335 |
Affbiotech |
200ul |
EUR 420 |
PGC1 alpha+beta Antibody |
49410-100ul |
SAB |
100ul |
EUR 399.6 |
PGC1 alpha+beta Antibody |
49410-50ul |
SAB |
50ul |
EUR 286.8 |
GSK3 alpha/beta antibody |
70R-51552 |
Fitzgerald |
100 ul |
EUR 344.4 |
Description: Purified Polyclonal GSK3 alpha/beta antibody |
GSK3 alpha/beta antibody |
70R-49831 |
Fitzgerald |
100 ul |
EUR 292.8 |
Description: Purified Polyclonal GSK3 alpha/beta antibody |
PKAC alpha/beta antibody |
70R-50246 |
Fitzgerald |
100 ul |
EUR 292.8 |
Description: Purified Polyclonal PKAC alpha/beta antibody |
PP2A alpha + beta Antibody |
49068-100ul |
SAB |
100ul |
EUR 399.6 |
PP2A alpha + beta Antibody |
49068-50ul |
SAB |
50ul |
EUR 286.8 |
GSK3 alpha / beta Antibody |
20-abx009185 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
GSK3 alpha/ beta Antibody |
DF6806 |
Affbiotech |
200ul |
EUR 420 |
JNK2 Antibody (alpha/beta) |
R32105 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: JNK2 is also known as MAPK9. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. Also, this gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Hsp90 alpha,beta Antibody |
abx139529-01mg |
Abbexa |
0.1 mg |
EUR 577.2 |
|
HSP90 alpha / beta Antibody |
abx444237-100ug |
Abbexa |
100 ug |
EUR 710.4 |
|
He strongly inspired younger reproductive biologists who labored in his laboratory, and applauded the world-wide distinction of his scholar and affiliate, R. Yanagimachi, as a specialist in mammalian fertilisation. Finally, Chang’s continued emotions in the direction of his homeland are contrasted with the actuality of his American life after 1945, itself a examine in poignancy.