One potential stressor that can affect preimplantation and postimplantation embryonic growth after in vitro fertilisation (IVF) is the pH of the human embryo culture medium, but no evidence exists to indicate which pH level is optimal for IVF.

Based on anecdotal evidence or mouse models, culture media manufacturers recommend a pH range of 7.2 to 7.4, and IVF laboratories routinely use a pH range of 7.25 to 7.3. Given the lack of randomised trials evaluating the effect of pH on live birth rate after IVF, this trial examines the effect of three different pH levels on the live birth rate.

This multicentre randomised trial will involve centres specialised in IVF in Egypt. Eligible couples for intracytoplasmic sperm injection (ICSI) will be randomised for embryo culture at pH 7.2, 7.3 or 7.4. The study is designed to detect 10 percentage points difference in live birth rate between the best and worst performing media with 93% power at a 1% significance level.

The primary outcome is the rate of live birth (delivery of one or more viable infants beyond the 20th week of gestation) after ICSI. Secondary clinical outcomes include biochemical pregnancy, clinical pregnancy, ongoing pregnancy, miscarriage, preterm births, birth weight, stillbirth, congenital malformation and cumulative live birth (within 1 year from randomisation).

Allele-In-One Human Blood Direct Lysis Buffer

ABP-PP-BD01500 500 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Human Blood Direct PCR Kit

ABP-PP-BD02100 100 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Human Blood Direct PCR Kit

ABP-PP-BD02500 500 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Mouse Tail Direct Lysis Buffer

ABP-PP-MT01100 100 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Mouse Tail Direct Lysis Buffer

ABP-PP-MT01500 500 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Mouse Tail Direct PCR Kit

ABP-PP-MT02100 100 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Mouse Tail Direct PCR Kit

ABP-PP-MT02500 500 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Human nonmethylated oligonucleotide,NON ELISA Kit

CN-04463H1 96T
EUR 452

Human nonmethylated oligonucleotide,NON ELISA Kit

CN-04463H2 48T
EUR 302

Human nonmethylated oligonucleotide,NON ELISA Kit

201-12-1892 96 tests
EUR 440
  • This nonmethylated oligonucleotide ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Oligonucleotide Binding Fold Containing 1 Protein

20-abx262451
  • EUR 328.00
  • EUR 6397.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg
  • Shipped within 5-10 working days.

Human nonmethylated oligonucleotide(NON)ELISA Kit

GA-E1908HM-48T 48T
EUR 289

Human nonmethylated oligonucleotide(NON)ELISA Kit

GA-E1908HM-96T 96T
EUR 466

Human nonmethylated oligonucleotide(NON)ELISA Kit

QY-E03624 96T
EUR 413

Testis-specific kinase substrate (TSKS) polyclonal antibody

ABP-PAB-10265 100 ug Ask for price
    • Product line: Miscellaneous
    • Brand:

Sentrin/SUMO-specific protease (SENP1) polyclonal antibody

ABP-PAB-11087 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Ubiquitin specific protease 6 (USP6) polyclonal antibody

ABP-PAB-11313 100 ug Ask for price
    • Product line: Miscellaneous
    • Brand:

ELISA kit for Human Nonmethylated oligonucleotide (NON)

KTE62600-48T 48T
EUR 354
  • Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids can b
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Nonmethylated oligonucleotide (NON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Nonmethylated oligonucleotide (NON)

KTE62600-5platesof96wells 5 plates of 96 wells
EUR 2252
  • Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids can b
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Nonmethylated oligonucleotide (NON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Nonmethylated oligonucleotide (NON)

KTE62600-96T 96T
EUR 572
  • Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids can b
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Nonmethylated oligonucleotide (NON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Sentrin/SUMO-specific protease 1 (SENP1) polyclonal antibody

ABP-PAB-10330 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 1 (SENP1) polyclonal antibody

ABP-PAB-10331 100 ug Ask for price
    • Product line: Proteases
    • Brand:

SUMO1/sentrin specific protease 6 (SENP6) polyclonal antibody

ABP-PAB-10338 100 ug Ask for price
    • Product line: Proteases
    • Brand:

SUMO1/sentrin specific protease 6 (SENP6) polyclonal antibody

ABP-PAB-10339 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Brain-specific angiogenesis inhibitor 1 (BAI1) polyclonal antibody

ABP-PAB-10421 100 ug Ask for price
    • Product line: Neuroscience
    • Brand:

Brain-specific angiogenesis inhibitor 2 (BAI2) polyclonal antibody

ABP-PAB-10422 100 ug Ask for price
    • Product line: Neuroscience
    • Brand:

Brain-specific angiogenesis inhibitor 3 (BAI3) polyclonal antibody

ABP-PAB-10423 100 ug Ask for price
    • Product line: Neuroscience
    • Brand:

Kallikrein 3 (KLK3, Prostate Specific Antigen, PSA) polyclonal antibody

ABP-PAB-10235 100 ug Ask for price
    • Product line: Miscellaneous
    • Brand:

Sentrin/SUMO-specific protease 5 (SENP5, MGC27076) polyclonal antibody

ABP-PAB-10336 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 5 (SENP5, MGC27076) polyclonal antibody

ABP-PAB-10337 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 2, N-terminus (SENP2) polyclonal antibody

ABP-PAB-10332 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 2, C-terminus (SENP2) polyclonal antibody

ABP-PAB-10333 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 3, N-terminus (SENP3) polyclonal antibody

ABP-PAB-10334 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 3, C-terminus (SENP3) polyclonal antibody

ABP-PAB-10335 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 7, N-terminus (SENP7) polyclonal antibody

ABP-PAB-10340 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 7, C-terminus (SENP7) polyclonal antibody

ABP-PAB-10341 100 ug Ask for price
    • Product line: Proteases
    • Brand:

OBFC1 Oligonucleotide Binding Fold Containing 1 Human Recombinant Protein

PROTQ9H668 Regular: 10ug
EUR 317
Description: OBFC1 Human Recombinant produced in E. coli is. a single polypeptide chain containing 391 amino acids (1-368) and having a molecular mass of 44.5kDa. OBFC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Human Suppressor of G2 allele of SKP1 homolog, SUGT1 ELISA KIT

ELI-52628h 96 Tests
EUR 824

Bovine Suppressor of G2 allele of SKP1 homolog, SUGT1 ELISA KIT

ELI-13668b 96 Tests
EUR 928

Mouse Suppressor of G2 allele of SKP1 homolog, Sugt1 ELISA KIT

ELI-18768m 96 Tests
EUR 865

Mouse Ig gamma- 2A chain C region, A allele, Ighg ELISA KIT

ELI-47186m 96 Tests
EUR 865

REDD1 Specific (REDD1 specific) Antibody

abx237228-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

TDRKH Specific (TDRKH specific) Antibody

abx238580-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Human TDRKH specific (TDRKH specific) ELISA Kit

abx259882-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Neuron Specific Peptide

5-01606 4 x 1mg Ask for price

KRT10-specific Antibody

abx234649-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Kv1.4-Specific Antibody

abx234664-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

LAMC3-Specific Antibody

abx234680-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

LATS2-Specific Antibody

abx234709-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

LC3A-Specific Antibody

abx234719-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

LC3B-Specific Antibody

abx234720-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

LDHA-Specific Antibody

abx234737-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

LDHB-Specific Antibody

abx234739-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

LDHC-Specific Antibody

abx234740-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Lin28A-specific Antibody

abx234784-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Lin28B-specific Antibody

abx234786-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

LRP2-Specific Antibody

abx234847-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

MAS1L-Specific Antibody

abx235020-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

MCL1L-specific Antibody

abx235054-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

MDM1-Specific Antibody

abx235076-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

MEF2C-Specific Antibody

abx235107-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

MYH10-Specific Antibody

abx235472-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

MYH4-Specific Antibody

abx235476-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

MYH7-specific Antibody

abx235478-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

MYOM1-Specific Antibody

abx235516-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

MYPN-Specific Antibody

abx235525-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

MYSM1-Specific Antibody

abx235527-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

NARFL-Specific Antibody

abx235553-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

NEB-Specific Antibody

abx235638-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Neogenin-Specific Antibody

abx235662-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

neurturin-Specific Antibody

abx235683-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

NFIX-Specific Antibody

abx235701-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

NOX3-Specific Antibody

abx235805-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Oct6-Specific Antibody

abx235965-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

PACS2-Specific Antibody

abx236099-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Palladin-Specific Antibody

abx236127-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

PAX1-Specific Antibody

abx236167-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

PAX8-Specific Antibody

abx236177-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

persephin-Specific Antibody

abx236323-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

PFKFB3-Specific Antibody

abx236339-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

PKM1-specific Antibody

abx236494-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

PKM2-specific Antibody

abx236495-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

PKM2-specific Antibody

abx236496-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

PLOD2-Specific Antibody

abx236552-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

POLR2B-Specific Antibody

abx236620-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

POTEA-Specific Antibody

abx236647-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

POTED-Specific Antibody

abx236648-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

POU3F3-Specific Antibody

abx236651-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

PPIA-Specific Antibody

abx236674-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

PPIF-Specific Antibody

abx236676-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

PPP1CB-Specific Antibody

abx236695-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

PPP1R11-Specific Antibody

abx236699-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

PSEN2-Specific Antibody

abx236853-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

PTH-Specific Antibody

abx236923-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

PYGM-Specific Antibody

abx236977-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

RAB11B-Specific Antibody

abx236989-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

RAB11-Specific Antibody

abx236994-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

RAB22A-specific Antibody

abx237005-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

RAB27A-specific Antibody

abx237011-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

RAB31-specific Antibody

abx237015-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

RAB3A-specific Antibody

abx237025-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

RAB3C-specific Antibody

abx237028-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

RAB5A-Specific Antibody

abx237039-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

RAB9A-Specific Antibody

abx237049-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

RAP1B-Specific Antibody

abx237109-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

RIM2-Specific Antibody

abx237301-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

RIMS4-Specific Antibody

abx237305-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

RIPK1-Specific Antibody

abx237313-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ROBO1-Specific Antibody

abx237372-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ROBO3-Specific Antibody

abx237374-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ROBO4-Specific Antibody

abx237375-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ROCK1-Specific Antibody

abx237377-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ROCK2-Specific Antibody

abx237379-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

RRM1-Specific Antibody

abx237495-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

RtcB-Specific Antibody

abx237515-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SEC61B-Specific Antibody

abx237691-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SENP5-Specific Antibody

abx237714-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SERINC2-Specific Antibody

abx237736-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SIRT2-Specific Antibody

abx237880-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SLC12A5-Specific Antibody

abx237908-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SLC25A6-Specific Antibody

abx237947-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SLIT2-Specific Antibody

abx237981-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SMYD1-Specific Antibody

abx238047-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Somatostatin-Specific Antibody

abx238109-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SPAG4-Specific Antibody

abx238142-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SPIN1-Specific Antibody

abx238178-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

SPTBN1-Specific Antibody

abx238204-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SRGAP3-Specific Antibody

abx238227-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ST8SIA2-Specific Antibody

abx238276-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

STEAP2-Specific Antibody

abx238317-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SURVIVIN-Specific Antibody

abx238403-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

SYN1-Specific Antibody

abx238416-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

TAF1-Specific Antibody

abx238484-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

TGFBR3-Specific Antibody

abx238645-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

TINAG-Specific Antibody

abx238712-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

TMF1-Specific Antibody

abx238796-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

TOP2A-Specific Antibody

abx238868-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Tuberin-Specific Antibody

abx239101-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

TWIST1-specific Antibody

abx239118-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

UBASH3A-Specific Antibody

abx239150-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

UBC9-Specific Antibody

abx239159-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

UBE2D1-Specific Antibody

abx239167-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

UBN1-Specific Antibody

abx239202-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

UNC5C-Specific Antibody

abx239263-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

UNC5D-Specific Antibody

abx239264-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

URB1-Specific Antibody

abx239286-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

WASF4-Specific Antibody

abx239469-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

YES1-Specific Antibody

abx239563-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ZIC4-Specific Antibody

abx239637-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

ZNF600-Specific Antibody

abx239718-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

ZNRF2-Specific Antibody

abx239746-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ACADL-Specific Antibody

abx230064-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

ADAM17-Specific Antibody

abx230139-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

ADRA1A-Specific Antibody

abx230177-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

ADRA2B-Specific Antibody

abx230179-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Embryo development outcomes include fertilisation, blastocyst formation and quality, and embryo cryopreservation and utilisation. The study was reviewed and approved by the Ethics Review Boards of the participating centres. Eligible women will sign a written informed consent before enrolment.

This study has an independent data monitoring and safety committee comprised international experts in trial design and in vitro culture. No plan exists to disseminate results to participants or health communities, except for the independent monitoring and safety committee of the trial.