One potential stressor that can affect preimplantation and postimplantation embryonic growth after in vitro fertilisation (IVF) is the pH of the human embryo culture medium, but no evidence exists to indicate which pH level is optimal for IVF.

Based on anecdotal evidence or mouse models, culture media manufacturers recommend a pH range of 7.2 to 7.4, and IVF laboratories routinely use a pH range of 7.25 to 7.3. Given the lack of randomised trials evaluating the effect of pH on live birth rate after IVF, this trial examines the effect of three different pH levels on the live birth rate.

This multicentre randomised trial will involve centres specialised in IVF in Egypt. Eligible couples for intracytoplasmic sperm injection (ICSI) will be randomised for embryo culture at pH 7.2, 7.3 or 7.4. The study is designed to detect 10 percentage points difference in live birth rate between the best and worst performing media with 93% power at a 1% significance level.

The primary outcome is the rate of live birth (delivery of one or more viable infants beyond the 20th week of gestation) after ICSI. Secondary clinical outcomes include biochemical pregnancy, clinical pregnancy, ongoing pregnancy, miscarriage, preterm births, birth weight, stillbirth, congenital malformation and cumulative live birth (within 1 year from randomisation).

Allele-In-One Human Blood Direct Lysis Buffer

ABP-PP-BD01500 500 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Human Blood Direct PCR Kit

ABP-PP-BD02100 100 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Human Blood Direct PCR Kit

ABP-PP-BD02500 500 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Mouse Tail Direct Lysis Buffer

ABP-PP-MT01100 100 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Mouse Tail Direct Lysis Buffer

ABP-PP-MT01500 500 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Mouse Tail Direct PCR Kit

ABP-PP-MT02100 100 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Allele-In-One Mouse Tail Direct PCR Kit

ABP-PP-MT02500 500 RXNS Ask for price
    • Product line: One-step Genotyping
    • Brand:

Human nonmethylated oligonucleotide,NON ELISA Kit

201-12-1892 96 tests
EUR 440
  • This nonmethylated oligonucleotide ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human nonmethylated oligonucleotide,NON ELISA Kit

CN-04463H1 96T
EUR 452

Human nonmethylated oligonucleotide,NON ELISA Kit

CN-04463H2 48T
EUR 302

Oligonucleotide Binding Fold Containing 1 Protein

20-abx262451
  • EUR 328.00
  • EUR 6397.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg
  • Shipped within 5-10 working days.

Human nonmethylated oligonucleotide(NON)ELISA Kit

GA-E1908HM-48T 48T
EUR 289

Human nonmethylated oligonucleotide(NON)ELISA Kit

GA-E1908HM-96T 96T
EUR 466

Human nonmethylated oligonucleotide(NON)ELISA Kit

QY-E03624 96T
EUR 413

Testis-specific kinase substrate (TSKS) polyclonal antibody

ABP-PAB-10265 100 ug Ask for price
    • Product line: Miscellaneous
    • Brand:

Sentrin/SUMO-specific protease (SENP1) polyclonal antibody

ABP-PAB-11087 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Ubiquitin specific protease 6 (USP6) polyclonal antibody

ABP-PAB-11313 100 ug Ask for price
    • Product line: Miscellaneous
    • Brand:

ELISA kit for Human Nonmethylated oligonucleotide (NON)

KTE62600-48T 48T
EUR 354
  • Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids can b
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Nonmethylated oligonucleotide (NON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Nonmethylated oligonucleotide (NON)

KTE62600-5platesof96wells 5 plates of 96 wells
EUR 2252
  • Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids can b
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Nonmethylated oligonucleotide (NON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Nonmethylated oligonucleotide (NON)

KTE62600-96T 96T
EUR 572
  • Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids can b
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Nonmethylated oligonucleotide (NON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Sentrin/SUMO-specific protease 1 (SENP1) polyclonal antibody

ABP-PAB-10330 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 1 (SENP1) polyclonal antibody

ABP-PAB-10331 100 ug Ask for price
    • Product line: Proteases
    • Brand:

SUMO1/sentrin specific protease 6 (SENP6) polyclonal antibody

ABP-PAB-10338 100 ug Ask for price
    • Product line: Proteases
    • Brand:

SUMO1/sentrin specific protease 6 (SENP6) polyclonal antibody

ABP-PAB-10339 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Brain-specific angiogenesis inhibitor 1 (BAI1) polyclonal antibody

ABP-PAB-10421 100 ug Ask for price
    • Product line: Neuroscience
    • Brand:

Brain-specific angiogenesis inhibitor 2 (BAI2) polyclonal antibody

ABP-PAB-10422 100 ug Ask for price
    • Product line: Neuroscience
    • Brand:

Brain-specific angiogenesis inhibitor 3 (BAI3) polyclonal antibody

ABP-PAB-10423 100 ug Ask for price
    • Product line: Neuroscience
    • Brand:

Kallikrein 3 (KLK3, Prostate Specific Antigen, PSA) polyclonal antibody

ABP-PAB-10235 100 ug Ask for price
    • Product line: Miscellaneous
    • Brand:

Sentrin/SUMO-specific protease 5 (SENP5, MGC27076) polyclonal antibody

ABP-PAB-10336 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 5 (SENP5, MGC27076) polyclonal antibody

ABP-PAB-10337 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 2, N-terminus (SENP2) polyclonal antibody

ABP-PAB-10332 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 2, C-terminus (SENP2) polyclonal antibody

ABP-PAB-10333 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 3, N-terminus (SENP3) polyclonal antibody

ABP-PAB-10334 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 3, C-terminus (SENP3) polyclonal antibody

ABP-PAB-10335 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 7, N-terminus (SENP7) polyclonal antibody

ABP-PAB-10340 100 ug Ask for price
    • Product line: Proteases
    • Brand:

Sentrin/SUMO-specific protease 7, C-terminus (SENP7) polyclonal antibody

ABP-PAB-10341 100 ug Ask for price
    • Product line: Proteases
    • Brand:

OBFC1 Oligonucleotide Binding Fold Containing 1 Human Recombinant Protein

PROTQ9H668 Regular: 10ug
EUR 317
Description: OBFC1 Human Recombinant produced in E. coli is. a single polypeptide chain containing 391 amino acids (1-368) and having a molecular mass of 44.5kDa. OBFC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Bovine Suppressor of G2 allele of SKP1 homolog, SUGT1 ELISA KIT

ELI-13668b 96 Tests
EUR 928

Mouse Suppressor of G2 allele of SKP1 homolog, Sugt1 ELISA KIT

ELI-18768m 96 Tests
EUR 865

Human Suppressor of G2 allele of SKP1 homolog, SUGT1 ELISA KIT

ELI-52628h 96 Tests
EUR 824

Mouse Ig gamma- 2A chain C region, A allele, Ighg ELISA KIT

ELI-47186m 96 Tests
EUR 865

TDRKH Specific (TDRKH specific) Antibody

abx238580-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

REDD1 Specific (REDD1 specific) Antibody

abx237228-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Human TDRKH specific (TDRKH specific) ELISA Kit

abx259882-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Neuron Specific Peptide

5-01606 4 x 1mg Ask for price

PFKFB3-Specific Antibody

DF12016 200ul
EUR 304
Description: PFKFB3-Specific antibody detects endogenous levels of PFKFB3-Specific.

PLOD2-Specific Antibody

DF12018 200ul
EUR 304
Description: PLOD2-Specific antibody detects endogenous levels of PLOD2-Specific.

FcRn-Specific Antibody

DF12607 200ul
EUR 304
Description: FcRn-Specific Antibody detects endogenous levels of FcRn-Specific.

NEB-Specific Antibody

DF12667 200ul
EUR 304
Description: NEB-Specific Antibody detects endogenous levels of NEB-Specific.

ST8SIA2-Specific Antibody

DF12754 200ul
EUR 304
Description: ST8SIA2-Specific Antibody detects endogenous levels of ST8SIA2-Specific.

CST2-Specific Antibody

DF12923 200ul
EUR 304
Description: CST2-Specific Antibody detects endogenous levels of CST2-Specific.

DLL1-Specific Antibody

DF12945 200ul
EUR 304
Description: DLL1-Specific Antibody detects endogenous levels of DLL1-Specific.

HSPG2-Specific Antibody

DF13077 200ul
EUR 304
Description: HSPG2-Specific Antibody detects endogenous levels of HSPG2-Specific.

Kv1.4-Specific Antibody

DF13119 200ul
EUR 304
Description: Kv1.4-Specific Antibody detects endogenous levels of Kv1.4-Specific.

LC3C-Specific Antibody

DF13125 200ul
EUR 304
Description: LC3C-Specific Antibody detects endogenous levels of LC3C-Specific.

MYH10-Specific Antibody

DF13164 200ul
EUR 304
Description: MYH10-Specific Antibody detects endogenous levels of MYH10-Specific.

MYOM1-Specific Antibody

DF13169 200ul
EUR 304
Description: MYOM1-Specific Antibody detects endogenous levels of MYOM1-Specific.

Neogenin-Specific Antibody

DF13183 200ul
EUR 304
Description: Neogenin-Specific Antibody detects endogenous levels of Neogenin-Specific.

MYH7-specific Antibody

DF12122 200ul
EUR 304
Description: MYH7-specific antibody detects endogenous levels of MYH7-specific.

CPT1C-specific Antibody

DF12150 200ul
EUR 304
Description: CPT1C-specific antibody detects endogenous levels of CPT1C-specific.

MYH4-Specific Antibody

DF12165 200ul
EUR 304
Description: MYH4-Specific antibody detects endogenous levels of MYH4-Specific.

CRLS1-Specific Antibody

DF12373 200ul
EUR 304
Description: CRLS1-Specific antibody detects endogenous levels of CRLS1-Specific.

PACS2-Specific Antibody

DF12441 200ul
EUR 304
Description: PACS2-Specific antibody detects endogenous levels of PACS2-Specific.

SEC61B-Specific Antibody

abx237691-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SENP5-Specific Antibody

abx237714-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SERINC2-Specific Antibody

abx237736-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SIRT2-Specific Antibody

abx237880-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SLC12A5-Specific Antibody

abx237908-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SLC25A6-Specific Antibody

abx237947-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SLIT2-Specific Antibody

abx237981-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SMYD1-Specific Antibody

abx238047-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Somatostatin-Specific Antibody

abx238109-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SPAG4-Specific Antibody

abx238142-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SPIN1-Specific Antibody

abx238178-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

SPTBN1-Specific Antibody

abx238204-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SRGAP3-Specific Antibody

abx238227-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ST8SIA2-Specific Antibody

abx238276-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

STEAP2-Specific Antibody

abx238317-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

SURVIVIN-Specific Antibody

abx238403-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

SYN1-Specific Antibody

abx238416-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

TAF1-Specific Antibody

abx238484-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

TGFBR3-Specific Antibody

abx238645-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

TINAG-Specific Antibody

abx238712-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

TMF1-Specific Antibody

abx238796-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

TOP2A-Specific Antibody

abx238868-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Tuberin-Specific Antibody

abx239101-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

TWIST1-specific Antibody

abx239118-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

UBASH3A-Specific Antibody

abx239150-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

UBC9-Specific Antibody

abx239159-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

UBE2D1-Specific Antibody

abx239167-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

UBN1-Specific Antibody

abx239202-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

UNC5C-Specific Antibody

abx239263-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

UNC5D-Specific Antibody

abx239264-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

URB1-Specific Antibody

abx239286-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

WASF4-Specific Antibody

abx239469-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

YES1-Specific Antibody

abx239563-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ZIC4-Specific Antibody

abx239637-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

ZNF600-Specific Antibody

abx239718-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

ZNRF2-Specific Antibody

abx239746-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

FGF16-Specific Antibody

abx233091-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

FMO2-specific Antibody

abx233169-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

FMO5-specific Antibody

abx233171-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

FOXH1-Specific Antibody

abx233196-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

FOXL2-Specific Antibody

abx233199-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

GAB3-Specific Antibody

abx233273-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

GABARAPL1-Specific Antibody

abx233276-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

GABARAPL2-Specific Antibody

abx233278-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

GAC-specific Antibody

abx233290-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

GATA4-Specific Antibody

abx233363-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

GEFT-Specific Antibody

abx233416-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

GLI2-Specific Antibody

abx233477-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

GLI3-Specific Antibody

abx233478-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

GPR101-Specific Antibody

abx233587-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

GPR123-Specific Antibody

abx233592-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

GPR139-Specific Antibody

abx233596-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

GPRASP1-Specific Antibody

abx233612-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

GPRIN3-Specific Antibody

abx233616-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

HBG1-Specific Antibody

abx233771-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

HBG1-Specific Antibody

abx233772-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

HBM-Specific Antibody

abx233773-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

HBQ1-Specific Antibody

abx233776-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

HBZ-Specific Antibody

abx233780-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

HDAC1-specific Antibody

abx233795-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

HDAC2-specific Antibody

abx233797-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

HDAC3-specific Antibody

abx233799-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

HDAC4-specific Antibody

abx233801-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

HDAC5-specific Antibody

abx233802-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

HDAC6-specific Antibody

abx233804-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

HIP1-Specific Antibody

abx233870-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

HMMR-Specific Antibody

abx233936-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

HNRNPUL2-Specific Antibody

abx233961-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

HRAS-Specific Antibody

abx234008-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

HSPG2-Specific Antibody

abx234063-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

IFITM1-Specific Antibody

abx234141-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

IFITM2-specific Antibody

abx234143-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

IGF1A-Specific Antibody

abx234168-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

IGF1B-Specific Antibody

abx234169-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

IGF1R-Specific Antibody

abx234170-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

IGF2R-Specific Antibody

abx234174-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

ING1-specific Antibody

abx234309-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ING3-specific Antibody

abx234312-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

ING4-specific Antibody

abx234314-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

ITPR1-specific Antibody

abx234425-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

KCNB1-Specific Antibody

abx234480-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

KGA-Specific Antibody

abx234520-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

KISS1R-Specific Antibody

abx234593-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

KLHL14-Specific Antibody

abx234614-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

KRT10-specific Antibody

abx234649-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Kv1.4-Specific Antibody

abx234664-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

LAMC3-Specific Antibody

abx234680-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

LATS2-Specific Antibody

abx234709-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

LC3A-Specific Antibody

abx234719-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

LC3B-Specific Antibody

abx234720-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

LDHA-Specific Antibody

abx234737-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

LDHB-Specific Antibody

abx234739-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Embryo development outcomes include fertilisation, blastocyst formation and quality, and embryo cryopreservation and utilisation. The study was reviewed and approved by the Ethics Review Boards of the participating centres. Eligible women will sign a written informed consent before enrolment.

This study has an independent data monitoring and safety committee comprised international experts in trial design and in vitro culture. No plan exists to disseminate results to participants or health communities, except for the independent monitoring and safety committee of the trial.